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Publications

  • "Mild and Ligand Free Pd(II)-Catalyzed Conjugate Additions to Hindered γ-Substituted Cyclohexenones", J. Jordan-Hore, J. N. Sanderson, A.-L. Lee, Org. Lett., 2012, ASAP, DOI:10.1021/ol300794a. Abstract

  • "Computational Studies on the Mechanism of the Gold(I)-Catalysed Rearrangement of Cyclopropenes", M. S. Hadfield, L. J. Häller, A.-L. Lee, S. A. Macgregor, J. A. T. O'Neill, A. M. Watson, Org. Biomol. Chem., 2012, DOI:10.1039/C2OB25183C. Abstract

  • "Divergent outcomes of gold(I)-catalyzed indole additions to 3,3-disubstituted cyclopropenes", P. C. Young, M. S. Hadfield, L. Arrowsmith, K. M. Macleod, R. J. Mudd, J. A. Jordan-Hore, A.-L. Lee, Org. Lett., 2012, 14, 898. Abstract

  • "1,3,4-Trisubstituted-1,2,3-Triazol-5-ylidene ‘Click’ Carbene Ligands: Synthesis, Catalysis and Self-Assembly", J. D. Crowley, A.-L. Lee, K. J. Kilpin, Aust. J. Chem. 2011, 64, 1118–1132. Review in the ‘Research Front’ issue on N-heterocyclic carbenes. Abstract

  • "Enantioselective Catalysis", A.-L. Lee, Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2011, 107, 369–389. Abstract

    - This review highlights significant advances in the field of enantioselective catalysis in 2010. Key advances in enantioselective gold-catalysed reactions, palladium-catalysed Heck reactions and alkene metathesis will be emphasised.

  • "Gold(I)-Catalysed Iodoalkoxylation of Allenes", A. Heuer-Jungemann, R. G. McLaren, M. S. Hadfield, A.-L. Lee, Tetrahedron, 2011, 67, 1609 - 1616. Abstract

  • "Gold(I)-catalysed Synthesis of Conjugated Trienes", M. S. Hadfield, A.-L. Lee, Chem. Commun., 2011, 47, 1333 - 1335. Abstract

  • "Gold(I) "Click" 1,2,3-Triazolylidenes: Synthesis, Self-assembly and Catalysis", K. J. Kilpin, U. S. D. Paul, A.-L. Lee, J. D. Crowley, Chem. Commun., 2011, 47, 328 - 330 (Emerging Investigators Theme Issue). Abstract

  • "Gold(I)-Catalysed Alcohol Additions to Cyclopropenes", M. S. Hadfield, J. T. Bauer, P. E. Glen, A.-L. Lee, Org. Biomol. Chem., 2010, 8, 4090 - 4095. Abstract

  • "Enantioselective Catalysis", A.-L. Lee, Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2010, 106, 428-446. Abstract

    - This review highlights significant advances in the field of enantioselective catalysis in 2009. Key advances in enantioselective gold-catalysed reactions and alkene metathesis are emphasised.

  • "Regioselective Synthesis of tert-Allylic Ethers via Gold(I)-Catalyzed Intermolecular Hydroalkoxylation of Allenes", M. S. Hadfield, A.-L. Lee, Org. Lett., 2010, 12, 484-487. Abstract
    • Highlighted in Synfacts 2010, 5, 0573, Contributors: H. Yamamoto and K. Griffin. Abstract

  • "Enantioselective Catalysis", A.-L. Lee, Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2009, 105, 421-439. Abstract

    -This review highlights significant advances in the field of asymmetric synthesis, with a mechanistic and catalysis flavour. Since this is the first review in Annual Reports B on this series, major advances from 2008 as well as a few older papers are covered. Key advances in enantioselective Heck couplings, alkene metathesis and catalysis by interlocked architectures are emphasised.

  • "Active metal template synthesis of rotaxanes, catenanes and molecular shuttles", J. D. Crowley, S. M. Goldup, A.-L. Lee, D. A. Leigh and R. T. McBurney, Chem. Soc. Rev., 2009, 38, 1530-1541. Abstract

  • "Gold Catalysed Reactions with Cyclopropenes", J. T. Bauer, M. S. Hadfield, A.-L. Lee, Chem. Commun., 2008, 6405-6407. Abstract

  • "Cadiot-Chodkiewicz Active Template Synthesis of Rotaxanes and Switchable Molecular Shuttles with Weak Intercomponent Interactions", J. Berna, S.M. Goldup, A.-L. Lee, D. A. Leigh, M. D. Symes, G. Teobaldi and F. Zerbetto, Angew. Chem. Int. Ed., 2008, 47, 4392-4396. Abstract
  • "[2]Rotaxanes through Palladium Active-Template Oxidative Heck Cross-Couplings", J. D. Crowley, K. Haenni, A.-L. Lee, D. A. Leigh, J. Am. Chem. Soc., 2007, 129, 12092-12093. Abstract
  • "A Catalytic Palladium Based Active-Metal Template Pathway to [2]Rotaxanes", J. Berna, J. D. Crowley, S. M. Goldup, K. Haenni, A.-L. Lee, D. A. Leigh, Angew. Chem. Int. Ed., 2007, 46, 5709-5713. Abstract
  • "Operationally Simple, Efficient and Diastereoselectvie Synthesis of Cis-2,6-Disubstituted-4-methylene Tetrahydropyrans Catalyzed by Triflic Acid", A. Puglisi A.-L. Lee, R. R. Schrock, A. H. Hoveyda, Org. Lett., 2006, 8, 1871-1874. Abstract
  • "Enantioselective Synthesis of Cyclic Enol Ethers and All-Carbon Quaternary Stereogenic Centres through Catalytic Asymmetric Ring-Closing Metathesis", A.-L. Lee, S. Malcolmson, A. Puglisi, R. R. Schrock, A. H. Hoveyda, J. Am. Chem. Soc., 2006, 128, 5153-5157. Abstract
  • "Integrated Microwave Assisted Synthesis and Solid-Supported Reagents", I.R. Baxendale, A.-L. Lee and S.V. Ley. In Microwave Assisted Organic Chemistry. Ed. J. P. Tierney and P. Lidstrom, Blackwells, 2005, ISBN 1405115602.
  • "The Synthesis of the Anti-malarial Natural Product Polysphorin and Analogues Using Polymer-supported Reagents and Scavengers", A-L. Lee, S.V. Ley, Org. Biomol. Chem., 2003, 1, 3957-3966. Abstract
  • "Microencapsulation of Osmium Tetroxide in Polyurea", S.V. Ley, C. Ramarao, A.-L. Lee, N. Östergaard, S.C. Smith, I.M. Shirley, Org. Lett., 2003, 5, 185-187. Abstract
  • "A Concise Synthesis of Carpanone Using Solid-Supported Reagents and Scavengers", I.R. Baxendale, A.-L. Lee, S.V. Ley, J. Chem. Soc., Perkin Trans. 1, 2002, 1850-1857. Abstract
  • "A Polymer-supported Iridium Catalyst for the Stereoselective Isomerisation of Double Bonds", I.R. Baxendale, A.-L. Lee, S.V. Ley, Synlett, 2002, 516-518. Abstract
  • "A Concise Synthesis of the Natural Product Carpanone Using Solid-Supported Reagents and Scavengers", I.R. Baxendale, A.-L. Lee, S.V. Ley, Synlett, 2001, 1482-1484; Errata, I.R. Baxendale, A.-L. Lee, S.V. Ley, Synlett, 2001, 2004. Abstract
  • "Polymer Supported Hydroxide", S.V. Ley, I.R. Baxendale and A.-L. Lee. In Electronic Encyclopedia of Reagents for Organic Synthesis Ed. L.A. Paquette, J. Wiley, 2001. Abstract
 

 

 

 

 

 
 

 

The photo above is of the Forth Bridge in Edinburgh. All photos © Ai-Lan Lee.